Fluoxetine hydrochloride:
Synonyms: (+-)-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanaminehydrochlorid;3-(p-trifluoromethylphenoxy)-n-methyl-3-phenylpropylaminehydrochloride;fontex;lilly110140;n-methyl-3-phenyl-3-(p-trifluoromethylphenoxy)-propylaminhydrochloride;FLUOXETINE-D5 HCL;FLUOXETINE-D5 HCL (PHENYL-D5);FLUOXETINE-D5 HYDROCHLORIDECAS: 56296-78-7
MF:C17H19ClF3NO
MW:345.79
EINECS:260-101-2
Product Categories:Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals;Serotonin;Amines;Aromatics;Isotope Labelled Compounds
Mol File:56296-78-7.mol
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Fluoxetine hydrochloride Chemical Properties |
Melting point | 158-159°C |
storage temp. | Store at RT |
CAS DataBase Reference | 56296-78-7(CAS DataBase Reference) |
EPA Substance Registry System | Benzenepropanamine, N-methyl-.gamma.-[4-(trifluoromethyl) phenoxy]-, hydrochloride(56296-78-7) |
Hazard Codes | Xn,N |
Risk Statements | 22-38-41-50 |
Safety Statements | 26-36/37/39-61-39 |
RIDADRÂ | 3249 |
RTECSÂ | UI4050000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Hazardous Substances Data | 56296-78-7(Hazardous Substances Data) |
Antidepressants Fluoxetine hydrochloride Usage And Synthesis:
1.Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI),it is adapted to the treatment of various depressive disorders, including mild or major depression, bipolar disorder depression, psychogenic depression and depressive neurosis. The mechanism is inhibiting neuronal uptake of serotonin from the synaptic cleft, increasing this neurotransmitter in the gap for practical use , thereby improving the emotional state,and treating depressive disorders. Common adverse reactions are dry mouth, loss of appetite, nausea, insomnia, fatigue, Â a few cases of anxiety and headaches are seen .
2.Because fluoxetine hydrochloride has longer half-life, patients whose liver and kidney function are poor or elderly patients, should appropriately reduce the dose. Children should be applied in accordance with the doctor's advice. Patients who has the history of epilepsy, pregnancy or lactation women should use with caution . If rash or fever occurs, the drug should be discontinued immediately and symptomatic treatment should be given. It  is not appropriate to be used with monoamine oxidase inhibitor (MAOI) ; if necessary, the drug should be discontinued after five weeks, before switching to a monoamine oxidase inhibitor (MAOI).
Related Antidepressant Pharmacuetical MaterialÂ
ParoxetineÂ
Sertraline
Fluvoxamine maleate,
Citalopram hydrobromide,
Duloxetine hydrochloride,
Venlafaxine hydrochloride   Â
Duloxetine
Bupropion
Trazodone
Nefazodone
Mirtazapine
Moclobemide
Escitalopram
Gabapentin Hydrochloride
Fluoxetine hydrochloride:
Synonyms: (+-)-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanaminehydrochlorid;3-(p-trifluoromethylphenoxy)-n-methyl-3-phenylpropylaminehydrochloride;fontex;lilly110140;n-methyl-3-phenyl-3-(p-trifluoromethylphenoxy)-propylaminhydrochloride;FLUOXETINE-D5 HCL;FLUOXETINE-D5 HCL (PHENYL-D5);FLUOXETINE-D5 HYDROCHLORIDECAS: 56296-78-7
MF:C17H19ClF3NO
MW:345.79
EINECS:260-101-2
Product Categories:Intermediates & Fine Chemicals;Isotope Labeled Compounds;Pharmaceuticals;Serotonin;Amines;Aromatics;Isotope Labelled Compounds
Mol File:56296-78-7.mol
Â
Fluoxetine hydrochloride Chemical Properties |
Melting point | 158-159°C |
storage temp. | Store at RT |
CAS DataBase Reference | 56296-78-7(CAS DataBase Reference) |
EPA Substance Registry System | Benzenepropanamine, N-methyl-.gamma.-[4-(trifluoromethyl) phenoxy]-, hydrochloride(56296-78-7) |
Hazard Codes | Xn,N |
Risk Statements | 22-38-41-50 |
Safety Statements | 26-36/37/39-61-39 |
RIDADRÂ | 3249 |
RTECSÂ | UI4050000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Hazardous Substances Data | 56296-78-7(Hazardous Substances Data) |
Antidepressants Fluoxetine hydrochloride Usage And Synthesis:
1.Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI),it is adapted to the treatment of various depressive disorders, including mild or major depression, bipolar disorder depression, psychogenic depression and depressive neurosis. The mechanism is inhibiting neuronal uptake of serotonin from the synaptic cleft, increasing this neurotransmitter in the gap for practical use , thereby improving the emotional state,and treating depressive disorders. Common adverse reactions are dry mouth, loss of appetite, nausea, insomnia, fatigue, Â a few cases of anxiety and headaches are seen .
2.Because fluoxetine hydrochloride has longer half-life, patients whose liver and kidney function are poor or elderly patients, should appropriately reduce the dose. Children should be applied in accordance with the doctor's advice. Patients who has the history of epilepsy, pregnancy or lactation women should use with caution . If rash or fever occurs, the drug should be discontinued immediately and symptomatic treatment should be given. It  is not appropriate to be used with monoamine oxidase inhibitor (MAOI) ; if necessary, the drug should be discontinued after five weeks, before switching to a monoamine oxidase inhibitor (MAOI).
Related Antidepressant Pharmacuetical MaterialÂ
ParoxetineÂ
Sertraline
Fluvoxamine maleate,
Citalopram hydrobromide,
Duloxetine hydrochloride,
Venlafaxine hydrochloride   Â
Duloxetine
Bupropion
Trazodone
Nefazodone
Mirtazapine
Moclobemide
Escitalopram
Gabapentin Hydrochloride
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